Molecular Basis of Inheritance

An analysis of chromosomal DNA using the Southern hybridization technique does not use:

1. Blotting
2. PCR
3. Electrophoresis
4. Autoradiography

Commonly used vectors for human genome sequencing are :

1. BAC and YAC
2. T/A Cloning Vectors
3. T-DNA
4. Expression Vectors

The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C. [figure]

1. A-translation B-extension C-Rosalind Franklin
2. A-translation B-transcription C-Erwin Chargaff
3. A-transcription B-translation C-Francis Crick
4. A-transcription B-replication C-James Watson

Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?

1. Transacetylase
2. Lactose permease and transacetylase
3. Lactose permease
4. -galactosidase

[figure] The figure gives an important concept in the genetic implication of DNA. Fill the blanks A, B and C.

1. A - Erwin Chargaff B - translation C - replication
2. A - Maurice Wilkins B - transcription C - translation
3. A - Francis Crick B - translation C - transcription
4. A - James Watson B - replication C - extension

Which of the following is not a property of the genetic code ?

1. Ambiguous
2. Universal
3. Degeneracy
4. Non-overlapping

In an inducible operon, the genes are :

1. usually expressed unless a signal turns them "off"
2. always expressed
3. never expressed
4. usually not expressed unless a signal turns them "on"

One of the most frequently used techniques in DNA fingerprinting is :-

1. SSCP
2. SCAR
3. VNTR
4. AFLP

Read the following four statements (A-D) : How many of the above statements are right ?

1. Four
2. Two
3. Three
4. One

What is it that forms the basis of DNA Fingerprinting ?

1. The relative proportions of purines and pyrimidines in DNA
2. The relative amount of DNA in the ridges and grooves of the fingerprints
3. The relative difference in the DNA occurrence in blood, skin and saliva
4. Satellite DNA occurring as highly repeated short DNA segments