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Molecular Basis of Inheritance

AIPMT 2010 (Mains)MCQEasy📈 Topic in 75% papers+4−1
Ques. 1AIPMT 2010 (Mains)

The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join -

  1. One nucleotide with another nucleotide
  2. One nitrogenous base with pentose sugar
  3. One nucleoside with another nucleoside
  4. One DNA strand with the other DNA strand

Answer

(1) One nucleotide with another nucleotide

Solution

As per NCERT, two nucleotides are linked through a 3'-5' phosphodiester linkage to form a dinucleotide; more nucleotides joined this way form a polynucleotide chain.

⇒ The base is joined to the pentose sugar by an N-glycosidic linkage, and the two DNA strands are held by hydrogen bonds.

Answer: (1)

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Ques. 2AIPMT 2010 (Mains)

The lac operon consists of -

  1. Three regulatory genes and three structural genes
  2. Four regulatory genes only
  3. Two regulatory genes and two structural genes
  4. One regulatory gene and three structural genes
Ques. 3AIPMT 2010 (Mains)

In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the -

  1. Dictyosomes
  2. Ribosomes
  3. Nucleus
  4. ER
Ques. 4AIPMT 2010 (Mains)

Which one of the following statements about the particular entity is true?

  1. Nucleosome is formed of nucleotides
  2. Centromere is found in animal cells, which produces aster during cell division
  3. The gene for producing insulin is present in every body cell
  4. DNA consists of a core of eight histones
Ques. 5AIPMT 2010 (Prelims)

Which one of the following does not follow the central dogma of molecular biology ?

  1. Mucor
  2. HIV
  3. Chlamydomonas
  4. Pea
Ques. 6AIPMT 2010 (Prelims)

The one aspect which is not a salient feature of genetic code, is its being –

  1. Specific
  2. Degenerate
  3. Ambiguous
  4. Universal
Ques. 7AIPMT 2010 (Prelims)

Select the two correct statements out of the four (A–D) statements given below about lac operon. The correct statements are :

  1. B and D
  2. A and B
  3. B and C
  4. A and C
Ques. 8AIPMT 2009

Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"?

  1. Nirenberg and Matthaei
  2. Morgan and Sturtevant
  3. Hershey and Chase
  4. Beadle and Tatum
Ques. 9AIPMT 2009

Semi-conservative replication of DNA was first demonstrated in:

  1. Drosophila melanogaster
  2. Streptococcus pneumoniae
  3. Salmonella typhimurium
  4. Escherichia coli
Ques. 10AIPMT 2009

Removal of introns and joining the exons in a defined order in a transcription unit is called:

  1. Transformation
  2. Capping
  3. Splicing
  4. Tailing
Ques. 11AIPMT 2009

What is not true for genetic code?

  1. It is nearly universal
  2. A codon in mRNA is read in a noncontiguous fashion
  3. It is degenerate
  4. It is unambiguous

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