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Molecular Basis of Inheritance

AIPMT 2010 (Mains)MCQMedium📈 Topic in 75% papers+4−1
Ques. 1AIPMT 2010 (Mains)

Which one of the following statements about the particular entity is true?

  1. Nucleosome is formed of nucleotides
  2. Centromere is found in animal cells, which produces aster during cell division
  3. The gene for producing insulin is present in every body cell
  4. DNA consists of a core of eight histones

Answer

(3) The gene for producing insulin is present in every body cell

Solution

(1) A nucleosome is formed of a histone octamer with negatively charged DNA wrapped around it — not of nucleotides alone. (incorrect)

(2) Asters are produced by the centrosome (centrioles), not by the centromere. (incorrect)

(3) Every somatic cell carries the complete genome, so the insulin gene is present in every body cell (it is expressed only in β-cells of the pancreas). (correct)

(4) The core of eight histones belongs to the nucleosome, not to DNA. (incorrect)

Answer: (3)

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Ques. 2AIPMT 2010 (Prelims)

Which one of the following does not follow the central dogma of molecular biology ?

  1. Mucor
  2. HIV
  3. Chlamydomonas
  4. Pea
Ques. 3AIPMT 2010 (Prelims)

The one aspect which is not a salient feature of genetic code, is its being –

  1. Specific
  2. Degenerate
  3. Ambiguous
  4. Universal
Ques. 4AIPMT 2010 (Prelims)

Select the two correct statements out of the four (A–D) statements given below about lac operon. The correct statements are :

  1. B and D
  2. A and B
  3. B and C
  4. A and C
Ques. 5AIPMT 2009

Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"?

  1. Nirenberg and Matthaei
  2. Morgan and Sturtevant
  3. Hershey and Chase
  4. Beadle and Tatum
Ques. 6AIPMT 2009

Semi-conservative replication of DNA was first demonstrated in:

  1. Drosophila melanogaster
  2. Streptococcus pneumoniae
  3. Salmonella typhimurium
  4. Escherichia coli
Ques. 7AIPMT 2009

Removal of introns and joining the exons in a defined order in a transcription unit is called:

  1. Transformation
  2. Capping
  3. Splicing
  4. Tailing
Ques. 8AIPMT 2009

What is not true for genetic code?

  1. It is nearly universal
  2. A codon in mRNA is read in a noncontiguous fashion
  3. It is degenerate
  4. It is unambiguous
Ques. 9AIPMT 2008

In the DNA molecule:

  1. the total amount of purine nucleotides and pyrimidine nucleotides is not always equal
  2. there are two strands which run antiparallel one in 5' 3' direction and other in 3' 5'
  3. there are two strands which run parallel in the 5' 3' direction
  4. the proportion of adenine in relation to thymine varies with the organism
Ques. 10AIPMT 2008

Which one of the following pairs of nitrogenous bases of nucleic acids is wrongly matched with the category mentioned against it?

  1. Thymine, Uracil — Pyrimidines
  2. Guanine, Adenine — Purines
  3. Uracil, Cytosine — Pyrimidines
  4. Adenine, Thymine — Purines
Ques. 11AIPMT 2008

Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid?

  1. UUA, UCA — Leucine
  2. AUG, ACG — Start/Methionine
  3. UAG, UGA — Stop
  4. GUU, GCU — Alanine

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