Molecular Basis of Inheritance

Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"?

1. Nirenberg and Matthaei
2. Morgan and Sturtevant
3. Hershey and Chase
4. Beadle and Tatum

Semi-conservative replication of DNA was first demonstrated in:

1. Drosophila melanogaster
2. Streptococcus pneumoniae
3. Salmonella typhimurium
4. Escherichia coli

Removal of introns and joining the exons in a defined order in a transcription unit is called:

1. Transformation
2. Capping
3. Splicing
4. Tailing

What is not true for genetic code?

1. It is nearly universal
2. A codon in mRNA is read in a noncontiguous fashion
3. It is degenerate
4. It is unambiguous

In the DNA molecule:

1. the total amount of purine nucleotides and pyrimidine nucleotides is not always equal
2. there are two strands which run antiparallel one in 5' 3' direction and other in 3' 5'
3. there are two strands which run parallel in the 5' 3' direction
4. the proportion of adenine in relation to thymine varies with the organism

Which one of the following pairs of nitrogenous bases of nucleic acids is wrongly matched with the category mentioned against it?

1. Thymine, Uracil — Pyrimidines
2. Guanine, Adenine — Purines
3. Uracil, Cytosine — Pyrimidines
4. Adenine, Thymine — Purines

Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid?

1. UUA, UCA — Leucine
2. AUG, ACG — Start/Methionine
3. UAG, UGA — Stop
4. GUU, GCU — Alanine

One turn of the helix in a B-form DNA is approximately -

1. 20 nm
2. 3.4 nm
3. 2 nm
4. 0.34 nm

One gene-one enzyme hypothesis was postulated by -

1. A. Garrod
2. Hershey and Chase
3. Beadle and Tatum
4. R. Franklin

Antiparallel strands of a DNA molecule means that-

1. The phosphate groups at the start of two DNA strands are in opposite position (pole)
2. One strand turns anti-clockwise
3. One strand turns clockwise
4. The phosphate groups of two DNA strands, at their ends, share the same position