Molecular Basis of Inheritance

Antiparallel strands of a DNA molecule means that-

1. The phosphate groups at the start of two DNA strands are in opposite position (pole)
2. One strand turns anti-clockwise
3. One strand turns clockwise
4. The phosphate groups of two DNA strands, at their ends, share the same position

Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis?

1. Neomycin
2. Erythromycin
3. Tetracycline
4. Streptomycin

Amino acid sequence, in protein synthesis is decided by the sequence of -

1. cDNA
2. mRNA
3. tRNA
4. rRNA

E. coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because -

1. They cannot transport lactose from the medium into the cell
2. They cannot synthesize functional -galactosidase
3. In the presence of glucose, E. coli cells do not utilize lactose
4. The lac operon is constitutively active in these cells

Telomerase is an enzyme which is a -

1. RNA
2. Repetitive DNA
3. Simple protein
4. Ribonucleoprotein

Protein synthesis in an animal cell occurs -

1. On ribosomes present in the nucleolus as well as in cytoplasm
2. On ribosomes present in cytoplasm as well as in mitochondria
3. Only on the ribosomes present in cytosol
4. Only on ribosomes attached to the nuclear envelope and endoplasmic reticulum

Which one of the following makes use of RNA as a template to synthesize DNA -

1. Reverse transcriptase
2. DNA dependent RNA polymerase
3. RNA polymerase
4. DNA polymerase

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called?

1. TATA box
2. GGTT box
3. CAAT box
4. AAAT box

Production of a human protein in bacteria by genetic engineering is possible because

1. The human chromosome can replicate in bacterial cell
2. The genetic code is universal
3. Bacterial cell can carry out the RNA splicing reactions
4. The mechanism of gene regulation is identical in humans and bacteria

During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and

1. RNA primers are involved
2. is facilitated by telomerase
3. moves in one direction of the site
4. moves in bi-directional way