Molecular Basis of Inheritance

Which one of the following makes use of RNA as a template to synthesize DNA -

1. Reverse transcriptase
2. DNA dependent RNA polymerase
3. RNA polymerase
4. DNA polymerase

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called?

1. TATA box
2. GGTT box
3. CAAT box
4. AAAT box

Production of a human protein in bacteria by genetic engineering is possible because

1. The human chromosome can replicate in bacterial cell
2. The genetic code is universal
3. Bacterial cell can carry out the RNA splicing reactions
4. The mechanism of gene regulation is identical in humans and bacteria

During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and

1. RNA primers are involved
2. is facilitated by telomerase
3. moves in one direction of the site
4. moves in bi-directional way

Which form of RNA has a structure resembling clover leaf ?

1. r-RNA
2. m-RNA
3. t-RNA
4. hn-RNA

During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the mRNA would be -

1. UAUGC
2. TCTGG
3. UATGC
4. TATGC

The following ratio is generally constant for a given species :-

1. A+CT+G
2. G+CA+T
3. A+GC+T
4. T+CG+A

DNA fingerprinting refers to :-

1. Techniques used for molecular analysis of different specimens of DNA
2. Analysis of DNA samples using imprinting devices
3. Molecular analysis of profiles of DNA samples
4. Techniques used for identification of fingerprints of individuals

The telomeres of eukaryotic chromosomes consist of short sequences of

1. Adenine rich repeats
2. Cytosine rich repeats
3. Thymine rich repeats
4. Guanine rich repeats

What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?

1. A polypeptide of 49 amino acids will be formed
2. A polypeptide of 25 amino acids will be formed
3. Two polypeptides of 24 and 25 amino acids will be formed
4. A polypeptide of 24 amino acids will be formed