The final proof for DNA as the genetic material came from the experiments of
- Griffith
- Hargobind Khorana
- Avery, MacLeod and McCarty
- Hershey and Chase
Answer
(4) Hershey and Chase
Solution
Griffith (1928) showed transformation but could not identify the transforming principle.
Avery, MacLeod and McCarty (1933–44) then showed that DNA is the transforming principle, but not all biologists were convinced.
As per NCERT, the unequivocal proof that DNA is the genetic material came from the experiments of Alfred Hershey and Martha Chase (1952) using bacteriophages with radioactive 32P (DNA) and 35S (protein).
Answer: (4)