Molecular Basis of Inheritance

Under which of the following conditions will there be no change in the reading frame of following mRNA? 5' AACAGCGGUGCUAUU 3'

1. Insertion of A and G at 4th and 5th positions respectively
2. Deletion of GGU from 7th, 8th and 9th positions
3. Insertion of G at 5th position
4. Deletion of G from 5th position

Which of the following features of genetic code does allow bacteria to produce human insulin by recombinant DNA technology?

1. Genetic code is nearly universal
2. Genetic code is specific
3. Genetic code is not ambiguous
4. Genetic code is redundant

Match the following genes of the Lac operon with their respective products : Select the correct option.

1. (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)
2. (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)
3. (a)-(i), (b)-(iii), (c)-(ii), (d)-(iv)
4. (a)-(iii), (b)-(i), (c)-(ii), (d)-(iv)

The experimental proof for semi-conservative replication of DNA was first shown in a

1. fungus
2. bacterium
3. plant
4. virus

Select the correct match :

1. Alec Jeffreys - Streptococcus pneumoniae
2. Alfred Hershey and Martha Chase - TMV
3. Matthew Meselson and F. Stahl - Pisum sativum
4. Francois Jacob and Jacques Monod - Lac operon

Select the correct match :

1. Ribozyme - Nucleic acid
2. F2 Recessive parent - Dihybrid cross
3. T.H. Morgan - Transduction
4. G. Mendel - Transformation

Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as

1. polysome
2. polyhedral bodies
3. plastidome
4. nucleosome

AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?

1. AGGUAUCGCAU
2. UGGTUTCGCAT
3. ACCUAUGCGAU
4. UCCAUAGCGUA

All of the following are part of an operon except

1. an operator
2. structural genes
3. an enhancer
4. a promoter

The final proof for DNA as the genetic material came from the experiments of

1. Griffith
2. Hargobind Khorana
3. Avery, MacLeod and McCarty
4. Hershey and Chase