Ques. 1AIPMT 2004
Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency?
- Luteinizing hormone – Failure of ovulation
- Insulin – Diabetes insipidus
- Thyroxine – Tetany
- Parathyroid – Diabetes mellitus
Answer
(1) Luteinizing hormone – Failure of ovulation
Solution
As per NCERT, LH surge in the middle of the menstrual cycle induces rupture of Graafian follicle and thereby ovulation.
⇒ Deficiency of LH ⇒ no LH surge ⇒ failure of ovulation. So pair (1) is correct.
∵ Insulin deficiency causes diabetes mellitus; diabetes insipidus is due to deficiency of ADH (vasopressin).
∵ Thyroxine deficiency causes goitre, cretinism and myxoedema; tetany is due to deficiency of parathyroid hormone (fall in blood Ca2+).
∴ Only 'Luteinizing hormone – Failure of ovulation' is correctly matched.
Answer: (1)